The term “autoimmunity” describes a disorder of the organism which leads to the body fighting and destroying its own cells. In order to arrive at the medical idea that the body fights itself, a lot of research was necessary. In the middle of the twentieth century, around 1957, the German-American immunologist Ernst Witebsky contributed to a paper attempting to define what an autoimmune disease is. He pointed out that autoimmunity can be associated with the body’s loss of immunological tolerance; that being the capacity of the body to ignore its own cells while at the same time reacting to invading cells like bacteria or viruses. Losing the capacity between the own and the other cells may result in the body fighting itself. Autoimmune diseases are not to be mixed up with immune deficiency diseases like HIV or Crohn’s disease; the latter having also been considered an autoimmune disease for a long time while now being more and more considered an immune deficiency.
In order to find out about the diseases and how they are caused and how they can be treated, medical institutions have to study the human body in great detail. With antibodies ordered on www.antibodies-online.com, researchers can perform the necessary tests. Some results are listed here.
Some of the most popular autoimmune diseases are diabetes mellitus type one, rheumatoid arthritis and coeliac disease. Diabetes type one results from an autoimmune destruction of beta cells which are responsible for producing the carbohydrate-regulating hormone insulin. Often the disease occurs at a very young age, and the diabetic person has to inject insulin throughout his or her whole life. For that reason, a healthy and reasonable nutrition is a core aspect for people suffering from diabetes. Rheumatoid arthritis is a systemic inflammatory disorder which involves the presence of autoantibodies known as rheumatoid factors among other things. The skin, joints and kidneys and the lungs may be affected by the inflammation causing pain and partly leading to immobility and deformity. The coeliac disease leads to an inflammation of the gastrointestinal tract and can lead to severe weight loss and blood anaemia.
As a result, autoimmune diseases can have different features and can affect different parts of the body.